The benzimidazole ring system in the title molecule, C 8 H 8 N 2 S, is planar The imidazole ring does not exhibit a delocalized aromatic bond system. Molecules are linked by N-HÁ Á ÁN hydrogen bonds along the c axis. The crystal structure is further stabilized by C-HÁ Á Á interactions.
Synthesis of 2-Methyl-1-[(5-methylfuran-2-yl)methyl]- and 2-Methyl-1-[(5-methylpyrrol-2-yl)methyl]-1H-benzimidazoles
✍ Scribed by Stroganova, T. A.; Redâkin, V. M.; Kovalenko, G. A.; Vasilin, V. K.; Krapivin, G. D.
- Book ID
- 121427405
- Publisher
- Springer US
- Year
- 2013
- Tongue
- English
- Weight
- 456 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0009-3122
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In the title compound, C 6 H 9 N 3 O 2 Se, which is a selenol substituent derivative of metronidazole, all bond lengths and angles are normal. The imidazole ring and nitro group make a dihedral angle of 6.6 (1) , while the N-C-C-Se torsion angle is 59.5 (8) .
## Abstract A useful approach for the synthesis of pharmacologically active tetrahydropyridinylbenzimidazoles is described. 2‐Pyridin‐3‐ylbenzimidazoles **3a‐d** have been synthesized by condensation of 3‐pyridinecarbox‐aldehyde **1** with substituted 1,2‐phenylenediamines **2a‐d** following oxidat
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