✦ LIBER ✦

Synthesis of 2-methoxy-2-methyl-3-{6-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]pyridin-3-yl}propanoic acid, a dual PPARα/γ agonist

✍ Scribed by Paul S. Humphries; Quyen-Quyen T. Do; David M. Wilhite

Book ID: 104096234
Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 291 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.01.113

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✦ Synopsis

Large quantities of an enantiomerically pure novel dual PPARa/c agonist were required. Three routes were successfully developed to achieve this goal, with the chosen route utilized to deliver 40 g of material.

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