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Synthesis of 2′-deoxy-2′-[18F]fluoro-β-D-arabinofuranosyl nucleosides, [18F]FAU, [18F]FMAU, [18F]FBAU and [18F]FIAU, as potential PET agents for imaging cellular proliferation: synthesis of [18F]labelled FAU, FMAU, FBAU, FIAU

✍ Scribed by Thomas J Mangner; Raymond W Klecker; Lawrence Anderson; Anthony F Shields


Book ID
117687926
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
218 KB
Volume
30
Category
Article
ISSN
0969-8051

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Synthesis of [18F]-labeled 2′-deoxy-2′-f
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 1 views

## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th