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Synthesis of 2-acylindole-3-acetic acids: a novel base-mediated indole synthesis

✍ Scribed by Kazunari Nakao; Yoshinori Murata; Hiroki Koike; Chikara Uchida; Kiyoshi Kawamura; Sachiko Mihara; Shigeo Hayashi; Rodney W. Stevens

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 93 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01879-3

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✦ Synopsis

An efficient and expedient synthetic route to 2-acylindole-3-acetic acids is described. This work first demonstrates a one-pot room-temperature indole ring construction via the in situ generation of indoline intermediate.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.