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Synthesis of 2-acetyl-1,4,5,6-tetrahydropyridine, a constituent of bread aroma

โœ Scribed by Buechi, George; Wuest, Hans

Book ID
126625366
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
311 KB
Volume
36
Category
Article
ISSN
0022-3263

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Synthesis of 1,2,4-trisubstituted-1,2,5,
Synthesis of 1,2,4-trisubstituted-1,2,5,6-tetrahydropyridines
โœ Meng-Yang Chang; Ming-Fang Lee; Nien-Chia Lee; Yu-Ping Huang; Chung-Han Lin ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 615 KB

A novel method for the synthesis of 1,2,4-trisubstituted-or 1,2,3,4-tetrasubstituted-1,2,5,6-tetrahydropyridine is presented. The process was carried out by the bromomethoxylation of 4-substituted-1,2,5,6-tetrahydropyridines 1 with N-bromosuccinimide (NBS) in methanol, dehydrobromination with 1,8-di