A new synthesis of substituted 1,4,5,6-tetrahydropyridines
β Scribed by I. A. Zaitsev; M. M. Shestaeva; V. A. Zagorevskii; E. I. Fedin
- Book ID
- 112334036
- Publisher
- Springer US
- Year
- 1971
- Tongue
- English
- Weight
- 204 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0009-3122
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π SIMILAR VOLUMES
A novel method for the synthesis of 1,2,4-trisubstituted-or 1,2,3,4-tetrasubstituted-1,2,5,6-tetrahydropyridine is presented. The process was carried out by the bromomethoxylation of 4-substituted-1,2,5,6-tetrahydropyridines 1 with N-bromosuccinimide (NBS) in methanol, dehydrobromination with 1,8-di
Arecoline and other arecaidine esters are semirigid derivatives of the reverse carboxy-analogue of acetylcholine with high muscarinic potencies and intrinsic activities'). Among the arecaidine esters the propargyl derivative 1 is more potent than arecoline and even acetylcholine'). Since the bioisos