𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of [2-14C] 3′-deoxythymidin-2′ -ENE (d4T) and [5–125I] 3′ -azido-2′, 3′-dideoxy-5-iodouridine: Potent inhibitors of human immunodeficiency virus (HIV-1)

✍ Scribed by Tai-Shun Lin; You-Song Gao; E. Michael August; He-Ying Qian; William H. Prusoff

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
235 KB
Volume
27
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Syntheses of [2-14C] 2,5′-anhydro-3′-azi
Syntheses of [2-14C] 2,5′-anhydro-3′-azido-3′-deoxythymidine and [2-14C] 2,5′-anhydro-3′-azido-2′,3′-dideoxy-5-iodouridine: Inhibitors of human immunodeficiency virus (HIV-1)
✍ Tai-Shun Lin; Mao-Chin Liu; E. Michael August; Evelyn M. Birks; William H. Pruso 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 300 KB

## Abstract The syntheses of [2‐^14^C] 2,5′‐anhydro‐3′‐azido‐3′‐deoxythymidine and [2‐^14^C] 2,5′‐anhydro‐3′‐azido‐2′,3′‐dideoxy‐5‐iodouridine in a one pot operation under mild conditions are described.

A stereospecific synthesis of 2′,3′-dide
A stereospecific synthesis of 2′,3′-dideoxy-β-l-cytidine (β-l-ddC), a potent inhibitor against human hepatitis B virus (HBV) and human immunodeficiency virus (HIV)
✍ Tai-Shun Lin; Mei-Zhen Luo; Mao-Chin Liu 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 258 KB

2',3'-Dideoxy-B-L-cytidine (p-L-ddC), a potent inhibitor against human hepatitis B virus (HBV) and human immunodeficiency virus (HIV), has been stexwsjwifically synthesized from Garabinose in 9 steps. Recently, 2',3'dideoxy-~D-cytidiie (ddC) has been shown to be a potent inhibitor of the replication

Synthesis of [carbonyl-14C]- and (methox
Synthesis of [carbonyl-14C]- and (methoxy-d3)-labeled N-[(2RS, 3RS)-1-benzyl-2-methyl-3-pyrrolidinyl] −5-chloro-2-methoxy-4-(methylamino) benzamide (YM-09151-2). A new potent neuroleptic agent
✍ Kazuharu Tamazawa; Hideki Arima 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 485 KB

## Abstract A new potent neuroleptic agent YM‐09151‐2, N‐[(2RS, 3RS)‐1‐benzyl‐2‐methyl‐3‐pyrrolidinyl]‐5‐chloro‐2‐methoxy‐4‐ (methylamino) benzamide (**10c**), was labeled with carbon‐14 and deuterium for biochemical studies such as metabolism and 14 pharmacokinetics. The synthesis of [carbonyl‐^14