## Abstract Reaction of adriamycinone with excess ^14^CH~3~Mgl and periodate cleavage of the resulting glycol (5) affords daunomycinone‐14‐^14^C (6). Bromination and hydrolysis of 6 gives adriamycinone‐14‐^14^C (8). Coupling of 6 and the 14‐0‐p‐anisyldiphenyl‐methyl derivative (9) with 1‐chloro‐3‐N
Synthesis of [14C]methylphosphonic difluoride
✍ Scribed by W. E. Bechtold; A. R. Dahl
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- French
- Weight
- 250 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2135
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📜 SIMILAR VOLUMES
14-14C-Adriamycin HC1 has been prepared from unlabeled adriamycin. The 14C-Diazald served as the source of the label. This synthesis does not require protection of the phenolic hydroxyl groups.
The synthesis of lanosterol [la] and desmosterol [Ira] Iabeled with 14C in the 25 position by a Wittig reaction between triphenyl-214C isopropylidene-phosphorane [IVb] and the corresponding aldehydes are described. The specijic activities obtained are, respectively, 0.539 mClmM and 0.752 mClmM and t
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The complete manuscript of this communication appears in: __Angew. Chem. Suppl. 1982__, 2010. DOI:10.1002/anie.198220100
## Abstract A convenient procedure to synthesize 2–^14^C‐dinitroso‐hexahydropyrimidine (DNHP) is described. The synthesis begines with the condensation of ^14^C‐formaldehyde and propylenediamine‐1,3 in benzene with azeotropic removal of water. The resulting bases are isolated from the reaction mixt