β Scribed by JR Harding; JA Bergin
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
ICI 185,282 ((SZ)-7-[(2RS, 4RS, 5SR)-4-o-Wdroxypheny1-Ztri fluoromethyl--1,3-d|~-'an-5--yl ]-~--hepteno|c acid), a novel thromboxane receptor antagonist, has been radiolabelled with 14C for use in metabolism studies. [14C]-ICI 185,282 (1), specific activity 23.8 mCi/mmol, radiochemical purity 98% wa
14C-Labelled satigrel, or 4-cyano-5-(4'-methoxy tring-U-14CI phenyl)-5-(4"methoxyphenyl)-4-pentenoic acid was synthesized for drug metabolism and pharmacokinetic studies using 4,4'-diniethoxy [ring-U-W ] benzophenone as the starting material. The radiochemical yield was 10.0%. The specific radioacti
The synthesis of 14C-labelled crotamiton, which is a fungicide, an insecticide as well as a scabicide is described. Starting from 2-bromonitrobenzene and Cu14CN, 2-toluidine, labelled with 14C at the methyl group was prepared by the following sequence of reactions : N O ~-C ~H L + -~~C O O H
## Abstract [^14^C]Aminoguanidine was synthesized by the reaction of hydrazine sulphate with barium [^14^C]cyanamide in a oneβstep synthesis, and conveniently isolated by crystallization as the bicarbonate salt. The yield was 32%.