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Synthesis of 14C-labelled bromocresol green and metacresol purple

✍ Scribed by P. Thourel; A. Vandais; J-P. Noel; J-P. Beaucourt

Publisher: John Wiley and Sons
Year: 1994
Tongue: French
Weight: 210 KB
Volume: 34
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580340310

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✦ Synopsis

Abstract

[methyl‐^14^C]‐Bromocresol green 1 was synthesized from [^14^C] ‐ methyl iodide in four steps via 3‐[methyl‐^14^C]‐methylanisole 3, [methyl‐^14^C]‐metacresol 4 and [methyl‐^14^C]‐metacresol purple 6. The overall yield of 1 from [^14^C] methyl iodide was 5.3% and the specific activity 112 mCi/mmol.

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