Synthesis of 14C-(carbonyl)-N-(4-iodo-2,6-diethylphenylcarbamoylmethyl)-iminodiacetic acid
✍ Scribed by Oscar R. Pozzi; Carlos P. Arciprete; Eduardo G. Gros; Aldo E. A. Mitta
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 168 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The synthesis of the N‐(4‐iodo‐2,6‐diethylphenylcarbamoylmethyl) iminodiacetic acid labelled with ^14^C at the carbonyl carbon atom which was required for metabolism studies is described. The complex formation between the title product and Tc‐99m is also presented.
📜 SIMILAR VOLUMES
## Abstract Synthesis of 6‐/N,N‐1′, 6′‐hexyleneformamidine‐^14^C/penicillanic acid /VII/ was carried out. N‐formyl‐^14^C‐hexamethyleneimine /II/ was obtained from formic‐14C acid and hexamethyleneimine /I/. The product was chlorinated with oxalyl chloride. The obtained N,N‐1, 6‐hexylenechloroformim
## Abstract In a first step, Δ1‐trans‐octenoic‐3‐^14^C acid was prepared by a Grignard reaction with BaCO~3~‐^14^C and 1‐bromo‐pentane, followed by reduction of the obtained hexanoic‐1‐^14^C acid to hexanal‐1‐^14^C via the n‐hexanol‐1‐^14^C. The produced hexanal‐1‐^14^C, by condensing with malonic
## Abstract 6‐n‐Propyl‐2‐thiouracil‐6−^14^C was prepared from sodium butyrate‐1−^14^C, with a radiochemical yield of 34%. Butyryl chloride‐1−^14^C was prepared from butyric acid‐1−^14^C and condensed with sodio ethylacetoacetate to yield ethyl β‐oxohexanoate‐β−^14^C. The β‐keto ester was condensed