𝔖 Bobbio Scriptorium
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Synthesis of 14C-anthralin

✍ Scribed by C. Brown; J. Eustache; J. P. Frideling; B. Shroot

Book ID
102371625
Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
342 KB
Volume
21
Category
Article
ISSN
0022-2135

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✦ Synopsis

1,P-dihydroxy-[30-14C]9-anthrone (anthralin) was synthesized in qood yield startinq from readily available 3-methoxy-2-(2-methoxybenzyl) -benzoic acid (2).

14C was introduced via carboxylation of the Griqnard derived from 3-bromo-2(2-methoxybenzyl) anisole. This, in turn, was obtained from (3) by a Curtius and Sandmeyer reaction sequence.

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