Synthesis of some disubstituted cyanoace
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Herbert F. Schwartz II; Lee F. Worrell; Jaime N. Delgado
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Article
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1967
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John Wiley and Sons
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English
โ 700 KB
A series of 17 cyanoacetamides was synthesized for pharrnacologic evaluation. Several synthetic methods were studied: C-alkylation, acylation of amines by ester, and acylation of amines by amides. The Galkylation of cyanoacetamides was investigated in several solvent systems using various bases, and