## Abstract A method is described for a no‐carrier‐added synthesis and purification of doubly‐labelled [5‐^125^I, U‐^14^C]‐iododeoxycytidine triphosphate. Iodination of ^14^C‐dCTP was achieved with a radiochemical yield of 80%. Separation and purification of the reaction product were accomplished b
Synthesis of 125I-labeled 14-iodo-9-tetradecynoic acid
✍ Scribed by C. A. Otto; L. E. Brown; D. M. Wieland; W. H. Beierwaltes
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 296 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
The synthesis and radioiodide exchange labelling of 14‐iodo‐9‐tetradecynoic acid (1), a potential suicide inhibitor of acyl‐CoA dehydrogenase or enoyl‐CoA isomerase, is presented. Tissue distribution data in dogs are reported.
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## Abstract A convenient small scale chemical synthesis of double labeled folic acid with ^13^C at positions C‐7 and C‐9 is reported. [1,3‐^13^C~2~] acetone was converted into folic acid in two steps, with [1, 1, 3]‐trichloroacetone as the labeled intermediate.
## Abstract The synthesis of isotopomers of phenylpyruvic acid, PPA, selectively labeled with hydrogen isotopes in the 3‐position of the side‐chain is reported. Three deuterium or tritium labeled isotopomers of L‐phenylalanine, L‐Phe, i.e. [(3__S__)‐^2^H]‐L‐, [(3__S__)‐^3^H]‐L‐, and doubly labeled