The chemical synthesis of double labelled mevalonolactone with carbon l a c at positions C-4 and C-6 is reported.
A new synthesis of double labeled [7, 9 -13C2] folic acid
β Scribed by Marlon Cowart; Christopher J. Falzone; Stephen J. Benkovic
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- French
- Weight
- 201 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-2135
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β¦ Synopsis
Abstract
A convenient small scale chemical synthesis of double labeled folic acid with ^13^C at positions Cβ7 and Cβ9 is reported. [1,3β^13^C~2~] acetone was converted into folic acid in two steps, with [1, 1, 3]βtrichloroacetone as the labeled intermediate.
π SIMILAR VOLUMES
2 -~h l o r o -[ l -~~C ] p r o p i o n y l chloride, phenyl-2-chloro-[l-13Clpropionate, 2-chloro-[ 1-13C] propan-1-01. 1-methyl-[ 2-I3C I ethylene oxide. SUMMARY 13 l-Methyl-[2-Clethylene oxide (I) is prepared in a four-step synthesis, I J starting from [l-Clpropionic acid. A method for an efficien
## Abstract The synthesis of [1,3,5β^13^C~3~]β and [2,4,6,7β^13^C~4~]benzoic acid (5a and 5b) from [2β^13^C]β and [3β^13^C]sodium pyruvate (1a and 1b), for __in vitro__ and __in vivo__ tracer studies using ^13^C nuclear magnetic resonance (NMR) spectroscopy, is reported. After condensation of 1 to
The total synthesis of the title compound from pyruvic aldehyde dimethyl acetal and ethyl [Z-lfClacetate is reported.