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A new synthesis of double labeled [7, 9 -13C2] folic acid

✍ Scribed by Marlon Cowart; Christopher J. Falzone; Stephen J. Benkovic


Publisher
John Wiley and Sons
Year
1994
Tongue
French
Weight
201 KB
Volume
34
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

A convenient small scale chemical synthesis of double labeled folic acid with ^13^C at positions C‐7 and C‐9 is reported. [1,3‐^13^C~2~] acetone was converted into folic acid in two steps, with [1, 1, 3]‐trichloroacetone as the labeled intermediate.


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