The title compound, C 18 H 20 ClNO 2 , has been synthesized by the reaction of 4-chlorobenzaldehyde, Meldrum's acid, dimedone and CH 3 NH 3 Cl(NaOAc) in ethanol under microwave irradiation. The pyridone ring adopts a screw-boat conformation and the cyclohexenone ring an envelope conformation.
Synthesis of 1,2,3,4,6,7,8,9-octahydropyrimido[4,5-b]quinoline-2,4-dione
✍ Scribed by M. Yu. Gavrilov; M. E. Konshin
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 304 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0009-3122
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In the title compound, C~20~H~25~N~3~O~5~S, the pyrrolidine ring is __trans__-fused to the dihydropyran ring. The pyrrolidine ring adopts a twist conformation and the dihydropyran ring is in an envelope conformation. The tosyl group is attached to the pyrrolidine ring in a biaxial position and its b
An efficient synthesis of novel spiro 2,3,7,8-tetrahydro-benzo[1,2-b:5,4-b 0 ]dipyran-4,6-dione and 2,3,8,9tetrahydro-benzo[1,2-b:4,3-b 0 ]dipyran-4,10-dione derivatives in high yields under microwave irradiation is described. The reaction was also studied under conventional heating conditions.