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Pyrimido[4,5-e](1,2,4)-triazolo[3,4-b](1,3,4)-thiadiazine-7,9(6H8H)-diones

✍ Scribed by H. K. Gakhar; J. K. Gill


Publisher
Springer Vienna
Year
1985
Tongue
English
Weight
213 KB
Volume
116
Category
Article
ISSN
0026-9247

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Stereospecific synthesis of 6,7-dihydro-
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The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines