Stereospecific synthesis of 6,7-dihydro-
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Yehia A. Ibrahim; Ahmed H. M. Elwahy; Ayman E. M. El-Fiky
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Article
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1994
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John Wiley and Sons
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English
β 319 KB
The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines