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Synthesis of 1,2,3,4-tetrahydro-4-pyridinones by heterocyclization of β-amino-β-arylacryloyloxiranes

✍ Scribed by A. M. Zvonok; N. M. Kuz'menok; V. A. Korshun; L. S. Stanishevskii


Book ID
104781384
Publisher
Springer US
Year
1989
Tongue
English
Weight
299 KB
Volume
25
Category
Article
ISSN
0009-3122

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✍ Frank Ungemach; Mike DiPierro; Robert Weber; James M. Cook 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 241 KB

The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4\_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corr