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Stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4-tetrahydro β-carbolines

✍ Scribed by Frank Ungemach; Mike DiPierro; Robert Weber; James M. Cook

Publisher: Elsevier Science
Year: 1979
Tongue: French
Weight: 241 KB
Volume: 20
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)95369-9

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✦ Synopsis

The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corresponding tetrahydro 8-carboline via catalytic hydrogenation.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v