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Synthesis and pharmacological properties of 1-R-2-[3′-R′-amino-2-hydroxypropyl]-1,2,3,4-tetrahydro-β-carbolines

✍ Scribed by L. P. Solomina; A. B. Sarkisyan; L. Sh. Pirdzhanov; É. M. Arzanunts; I. S. Sarkisyan; K. Zh. Markaryan; A. V. Pogosyan; É. A. Markaryan


Book ID
112400216
Publisher
Springer
Year
1990
Tongue
English
Weight
336 KB
Volume
24
Category
Article
ISSN
0091-150X

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✍ Frank Ungemach; Mike DiPierro; Robert Weber; James M. Cook 📂 Article 📅 1979 🏛 Elsevier Science 🌐 French ⚖ 241 KB

The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4\_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corr