Synthesis of 1,2-dihydroquinolin-2-ylphosphonates and 1,2-dihydroisoquinolin-1-ylphosphonates via three-component reactions
β Scribed by Ahmad Shaabani, Afshin Sarvary, Sajjad Mousavi-Faraz, Seik Weng Ng
- Book ID
- 113051501
- Publisher
- Springer Vienna
- Year
- 2011
- Tongue
- English
- Weight
- 383 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0026-9247
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A tandem four-component reaction of 2-bromobenzaldehyde, alkyne, amine, and diethyl phosphite catalyzed by the combination of palladium and copper salts provides a facile and efficient route to 1,2-dihydroisoquinolin-1-ylphosphonate. A cascade Sonogashira-intramolecular cyclization-nucleophilic addi
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