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Synthesis of (±) 1,2-dideoxy-1,2-diamino-myo-inositol

✍ Scribed by Philippe Guédat; Bernard Spiess; Gilbert Schlewer


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
204 KB
Volume
35
Category
Article
ISSN
0040-4039

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Both enantiomers of dideoxyfluoroamino inositols (+)-9 and (-)-9 were synthesized from bromocyclohexadiene cLv-diol I obtained by microbial oxidation of bromobenzene with toluene dioxygenase. Selective introduction of the amino group was achieved through S~2 displacement of trifates 7, l l. Fluorine