ChemInform Abstract: Synthesis of 1-O-(2-Oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol and 3,5-Dideoxy-1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol as Prodrugs of Inositolmonophosphatase Ligands.
β Scribed by L. SCHMITT; B. SPIESS; G. SCHLEWER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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An improved procedure for the preparation of 1,2-O-isopropylidene-nqVo-inositol is described. Racemic 1,4-di-O-benzyl-2,3-O-isopropylidene-myo-inositol was prepared by tinmediated benzylation of 1,2-0-isopropylidene-myo-inositol and resolved readily by crystalk sation of the o-camphanates. The use o