Synthesis of 1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol and 3,5-dideoxy-1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol as prodrugs of inositolmonophosphatase ligands
β Scribed by Laurent Schmitt; Bernard Spiess; Gilbert Schlewer
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 200 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Synthesis of l~).(2.0xo-Benzc,1;3,2-Dioxaphosphaocan-2.yl).Myo-Inositol
and 3,5-Dideoxy-l~)-(2-Oxo-Benzo-l$~2-Dioxaphosphaocan-2-yl) .Myo.
π SIMILAR VOLUMES
A convenient route for the synthesis of pure 1,2-dipalmitoyl-x-glycer-3-yl-D-w-inositol l-phosphate is presented. Phosphatidylinositol (la), which is one of a number of phospholipids found in the membranes of animal cells, is a key intermediate for the production of the intracellular second messenge
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