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Synthesis of 1,2- and 1,3-cyclic phospholipid conjugates of N1-(2-furanidyl)-N3-(2-hydroxyethyl)-5-fluorouracil

✍ Scribed by Zhang Cheng-Xiang; Zhang Zhong-Biao; Chen Huan-Ming; Tang Chu-Chi; Chen Ru-Yu

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 152 KB
Volume: 9
Category: Article
ISSN: 1042-7163
DOI: 10.1002/(sici)1098-1071(1998)9:3<295::aid-hc3>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

The conjugates of cyclic glycerolphospholipids and N 1 -(2-furanidyl)-N 3 -(2-hydroxyethyl)-5fluorouracil have been synthesized by a one-pot procedure. The hexaethylphosphorus triamide activated by a catalytic amount of iodine was used as the phosphorylating and cyclizing reagent.

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