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SYNTHESIS OF 1,1-BIS(HYDROXYMETHYL) CYCLOPROPANES

✍ Scribed by Verhe, R.; Courtheyn, D.; Kimpe, N. De; Buyck, L. De; Thierie, R.; Caenegem, L. Van; Schamp, N.


Book ID
120646576
Publisher
Taylor and Francis Group
Year
1981
Tongue
English
Weight
208 KB
Volume
13
Category
Article
ISSN
0030-4948

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Stereoselective synthesis of cyclopropan
✍ Siren Neset; HΓ₯kon Hope; Kjell Undheim πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 756 KB

Conformationally constrained bis(glycines) as trans derivatives of cyclopropane have been prepared in stereoselective syntheses. (S)-4-Benzyl-2-oxazolidinone was used as a chiral auxiliary, trisyl azide was the electrophilic source of amine nitrogen. Four stereogenic centers were created. A related