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Synthesis of 1,1-bis(1,2,4-triazol-1-yl)-based potential aromatase inhibitors

✍ Scribed by Alan R. Katritzky; Alfredo Pastor; Michael V. Voronkov

Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
229 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Reactions of bis‐(1,2,4‐triazolyl) sulfoxide 2 with various carbonyl compounds 3 led to the formation of twelve corresponding 1,1 ‐bis‐(1,2,4‐triazolyl) compounds, with structures resembling closely some previously prepared aromatase inhibitors.

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