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Synthesis of 10-Hydroxycamptothecin: Evaluation of New Moderators for the Chemoselective Reduction of Camptothecin

✍ Scribed by Sekhar, N. M.; Anjaneyulu, Yerramilli; Acharyulu, Palle V. R.


Book ID
121869458
Publisher
Taylor and Francis Group
Year
2011
Tongue
English
Weight
261 KB
Volume
41
Category
Article
ISSN
0039-7911

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Synthesis of a New Class of Camptothecin Derivatives, the Long-Chain Fatty Acid Esters of 10-Hydroxycamptothecin, as a Potent Prodrug Candidate, and Their in vitro Metabolic Conversion of Carboxylesterases. -The Friedlaender condensation strategy is used for the construction of the quinoline system