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ChemInform Abstract: Synthesis of 10-Hydroxycamptothecin: Evaluation of New Moderators for the Chemoselective Reduction of Camptothecin.

โœ Scribed by N. M. Sekhar; Yerramilli Anjaneyulu; Palle V. R. Acharyulu


Publisher
John Wiley and Sons
Year
2012
Weight
23 KB
Volume
43
Category
Article
ISSN
0931-7597

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Synthesis of a New Class of Camptothecin Derivatives, the Long-Chain Fatty Acid Esters of 10-Hydroxycamptothecin, as a Potent Prodrug Candidate, and Their in vitro Metabolic Conversion of Carboxylesterases. -The Friedlaender condensation strategy is used for the construction of the quinoline system