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Synthesis of 1-3H-3, 3-dimethylallyl pyrophosphate

✍ Scribed by E. Cardemil; O. Cori

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
247 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

3, 3‐Dimethylallyl pyrophosphate (DMAPP) Labeled with ^3^H on C‐1 was prepared from the corresponding acid by esterification, reduction of the methyl ester with LiAl^3^H~4~ and pyrophosphorylation of the radioactive alcohol.

The products were purified by ion‐exchange chromatography, yielding a single radioactive compound. Phosphorus analysis and gas chromatography showed that the final product was DMAPP.

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