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Synthesis of 1-(2-Chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-Amino-Substituted and Their Biological Evaluation.

โœ Scribed by Silvia Schenone; et al. et al.


Publisher
John Wiley and Sons
Year
2004
Weight
104 KB
Volume
35
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of 4-Subs
โœ M. L. TAHA; H. B. LAZREK ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act