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ChemInform Abstract: Synthesis and Biological Activity of 4-Substituted 1-[1-(2-Hydroxyethoxy)methyl-1,2,3-triazol-(4 and 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines.

โœ Scribed by O. Moukha-Chafiq; M. L. Taha; H. B. Lazrek; C. Pannecouque; M. Witvrouw; E. De Clercq; J. L. Barascut; J. L. Imbach


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of 4-Subs
โœ M. L. TAHA; H. B. LAZREK ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB

Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act