✦ LIBER ✦

Synthesis of 1-0-[(3S,4R)-3-hydroxytetrahydrofuran-4-yl]-α-D-glucopyranoside 3,4,3′-trisphosphate as a novel potent IP3 receptor ligand

✍ Scribed by Kazuya Tatani; Satoshi Shuto; Yoshihito Ueno; Akira Matsuda

Book ID: 104259467
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 280 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)00954-x

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✦ Synopsis

1-0-[(3S,4R)-3-Hydroxytetrahydrofuran-4-yl]-~-D-glucopyranoside 3,4,3'trisphosphate

(5) was designed and synthesized as a novel IP3 receptor ligand. This compound bound strongly to IP3 receptor from porcine cerebella with an affinity comparable to that of IP3.

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