𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2-exo-2-(2‘,3‘-Disubstituted 5‘-pyridinyl)-7-azabicyclo[2.2.1]heptanes: Epibatidine Analogues

✍ Scribed by Carroll, F. Ivy; Lee, Jeffrey R.; Navarro, Hernán A.; Ma, Wei; Brieaddy, Lawrence E.; Abraham, Philip; Damaj, M. I.; Martin, Billy R.


Book ID
111869157
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
104 KB
Volume
45
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of a radiotracer for studying
✍ Andrew Horti; Hayden T. Ravert; Edythe D. London; Robert F. Dannals 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 585 KB

The radiochemical synthesis of (+/-)-exo-2-(2-[18F]fluoro-5-pyridyl)-7azabicyclo[2.2. llheptane ([W'lI\_) was accomplished by Kryptofixa 222 assisted nucleophilic no-carrier-added [18F]fluorination of (+/-)-exo-2-(2-bromo-5-pyridyl)-7-azabicyclo[2.2.1] heptane (h). The average radiochemical yield of

Radiosynthesis of 2-exo-(2′-[18F]Fluoro-
✍ Gaëlle Roger; Françoise Hinnen; Héric Valette; Wadad Saba; Michel Bottlaender; F 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 189 KB

2-exo-(2 0 -Fluoro-3 0 -(4-fluorophenyl)-pyridin-5 0 -yl)-7-azabicyclo[2.2.1]heptane (F 2 PhEP), a novel, epibatidine-based, a4b2-selective nicotinic acetylcholine receptor antagonist of low toxicity, as well as the corresponding N-Boc-protected chloro-and bromo derivatives as precursors for labelli