Inside Cover: Synthesis, Inhibition Pote
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Christian Eberle; Johannes A. Burkhard; Bernhard Stump; Marcel Kaiser; Reto Brun
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Article
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2009
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John Wiley and Sons
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English
⚖ 467 KB
The inside cover picture shows a modeled structure of a novel competitive inhibitor of trypanothione reductase (TR) in the active site of the enzyme. TR is unique to trypanosomatid parasites and a target for lead discovery programs. The parasites depicted show the high accumulation of the fluorescen