Synthesis, in vitro and in vivo Evaluation of a Delivery System for Targeting Anticancer Drugs to the Brain
β Scribed by Magda A. El-Sherbeny; Huda S. Al-Salem; Maha A. Sultan; Mahasen A. Radwan; Hassan A. Farag; Hussein I. El-Subbagh
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 148 KB
- Volume
- 336
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
There has been some evidence that mixed triglycerides formed from coupling of drugs to diglycerides exhibit physicochemical and absorption as natural Wiglycerides. Drugs which lack carboxyl groups, allowing the direct formation of an ester bond with a diglyceride, can be bound via spacers such as su
## Abstract ## Objective Glomerular mesangial cells are active participants in the pathogenesis of lupus glomerulonephritis (GN). Thus, targeted delivery of therapeutic agents to mesangial cells would be an attractive approach to treatment. However, lack of known unique mesangial cell surface mark
We have evaluated the use of four different positive control compounds for assessing UDS in monkey hepatocytes and have found three of these, methylmethanesulfonate, benzo[a]pyrene, and dimethylbenz[a]anthracene, to produce strong positive responses in vitro. Dimethylnitrosamine induced only weak re