In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent
✦ LIBER ✦
Synthesis, cytotoxicity, and structure–activity insight ofNH- andN-methyl-3,5-bis-(arylidenyl)-4-piperidones
✍ Scribed by Matthew Gregory, Armaan Dandavati, Megan Lee, Samuel Tzou…
- Book ID
- 120908747
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 697 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1054-2523
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## Abstract 3,5‐Dimethyl‐5‐(4‐pyridyl)hydantoin (L) and its platinum(II) and platinum(IV) complexes with the general formula __cis__‐[PtL~2~X~2~] · __n__ H~2~O and [PtL~2~Cl~4~], where XCl, I and __n__ = 2‐4 were synthesized. A new Pt(IV) complex with 5‐methyl‐5‐(4‐pyridyl)hydantoin (L′) with the