𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis, characterization and in vitro hydrolysis studies of ester and amide prodrugs of dexibuprofen

✍ Scribed by Zaman Ashraf, Muhammad Imran, Shahid Amin

Book ID
118778019
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
346 KB
Volume
21
Category
Article
ISSN
1054-2523

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Novel amides and esters prodrugs of olme
Novel amides and esters prodrugs of olmesartan: Synthesis, bioconversion, and pharmacokinetic evaluation
✍ Jin-Hun Park; Jeong-Soo Chang; Mohammed I. El-Gamal; Won-Kyoung Choi; Woong San πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 560 KB

Synthesis of novel amides and esters prodrugs of olmesartan is described. Their in vitro stability in rat plasma was tested. The results showed that the ester derivative IIa with n-octyl substituted dioxolone moiety was rapidly converted into olmesartan within 30 min. The pharmacokinetic parameters