## Abstract A severe limitation in cancer therapy is the often insufficient differentiation between malign and benign tissue using known chemotherapeutics. One approach to decrease side effects is antibodyβdirected enzyme prodrug therapy (ADEPT). We have developed new glycosidic prodrugs such as (β
β¦ LIBER β¦
Synthesis, Characterization and Biological Evaluation of Succinate Prodrugs of Curcuminoids for Colon Cancer Treatment
β Scribed by Wichitnithad, Wisut; Nimmannit, Ubonthip; Wacharasindhu, Sumrit; Rojsitthisak, Pornchai
- Book ID
- 115506126
- Publisher
- Molecular Diversity Preservation International
- Year
- 2011
- Tongue
- English
- Weight
- 197 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1420-3049
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Asymmetric Synthesis and Biological Eval
Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy
β
Lutzβ
F. Tietze; J.β
Marian vonβ
Hof; Birgit Krewer; Michael MΓΌller; Felix Major; H
π
Article
π
2008
π
John Wiley and Sons
π
English
β 390 KB
π 1 views
Synthesis and biological evaluations of
β
Legigan, Thibaut; Clarhaut, Jonathan; Renoux, Brigitte; Tranoy-Opalinski, Isabel
π
Article
π
2013
π
Elsevier Science
π
French
β 547 KB
Computational and Biological Evaluation
β
Pavel Pospisil; Houari Korideck; Ketai Wang; Yongliang Yang; Lakshmanan K. Iyer;
π
Article
π
2012
π
John Wiley and Sons
π
English
β 699 KB
Synthesis and Biological Evaluation of N
β
Ling, Yong; Wang, Xuemin; Zhu, Hongyan; Wang, Zhiqiang; Xu, Chenjun; Wang, Xinya
π
Article
π
2014
π
John Wiley and Sons
π
English
β 361 KB
Synthesis and Biological Evaluation of N
β
LutzΒ F. Tietze; Tobias Herzig; Tim Feuerstein; Ingrid Schuberth
π
Article
π
2002
π
John Wiley and Sons
π
English
β 226 KB
π 2 views
This paper describes novel seco-analogues 25-27 of the cytotoxic antibiotic CC-1065 (1) and their prodrugs 5, 6a, and 6b, for antibody-directed enzyme prodrug therapy (ADEPT). The partially hydrogenated seco-CCI-analogue 7 and the corresponding methyl-CCI analogues 8a and 8b were synthesized by alky
Synthesis and biological evaluation of r
β
Cassia S. Mizuno; Shiby Paul; Nanjoo Suh; Agnes M. Rimando
π
Article
π
2010
π
Elsevier Science
π
English
β 283 KB