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Synthesis, Anion-Binding Properties, and In Vitro Anticancer Activity of Prodigiosin Analogues

โœ Scribed by Jonathan L. Sessler; Leah R. Eller; Won-Seob Cho; Sergios Nicolaou; Apolonio Aguilar; Jeong Tae Lee; Vincent M. Lynch; Darren J. Magda


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
127 KB
Volume
117
Category
Article
ISSN
0044-8249

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Synthesis, Anion-Binding Properties, and
โœ Jonathan L. Sessler; Leah R. Eller; Won-Seob Cho; Sergios Nicolaou; Apolonio Agu ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 127 KB ๐Ÿ‘ 2 views

Prodigiosins, for example, 1 and 2, are a family of naturally occurring tripyrrolic red pigments that were first isolated in the 1930s from microorganisms including Serratia and Streptomyces and are characterized by a common pyrrolylpyrromethene skeleton. [1] These molecules, especially prodigiosin

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## Abstract A series of novel compounds **7โ€“43** were prepared __via__ the condensation of enaminones **4aโ€“h** and the guanidines carbonate **6aโ€“f**. The structures of these newly synthesized compounds were confirmed by ^1^Hโ€NMR, MS, EA and IR. All the compounds were tested for their cytotoxic acti