## Abstract magnified image Substituted 4‐(5‐alkyl‐thiazol‐2‐ylmethyl)‐3,4‐dihydro‐2__H__‐1,4‐benzoxazines and 5‐(2,3‐dihydro‐1,4‐benzoxazin‐4‐ylmethyl)‐4‐methyl‐1‐phenyl‐1__H__‐pyrazol‐3‐ylamines were prepared by the reaction of (2,3‐dihydro‐1,4‐benzoxazin‐4‐yl)‐acetic acid methyl ester and some
Synthesis and κ binding affinity of 1-(pyrrolidin-1-ylmethyl)-2-(N-methyl)-4-[(3,4-dichloro)phenyl]-1,2,3,4 tetrahydroisoquinolin-3(2H)-ones
✍ Scribed by GA Pinna; E Gavini; G Cignarella; S Scolastico; P Fadda
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 513 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0223-5234
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📜 SIMILAR VOLUMES
We have developed a number of efficient protocols for the facile synthesis of 1,2,3,4-tetrahydroisoquinolin-1-ones. This synthetic methodology allowed concise and efficient exploration of the SAR in all areas of the molecule. A number of these methods proved to be versatile, efficient and amenable t
When N-chloroacetyl-3-hydroxybenzylamine (37) in aqueous acetonitrile was irradiated, both ortho and para photocyclizations with reference to the OH group occurred to give 7-and 5 -hydroxy -3 -oxo -1,2,3,4tetrahydroisoquinolines ($2, 53). Similarly, 1 -methylisoquinoline derivatives (54, 55) were sy