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Synthesis and studies of calcium channel blocking and antioxidant activities of novel 4-pyridinium and/or N-propargyl substituted 1,4-dihydropyridine derivatives

✍ Scribed by Rucins, Martins; Kaldre, Dainis; Pajuste, Karlis; Fernandes, Maria A.S.; Vicente, Joaquim A.F.; Klimaviciusa, Linda; Jaschenko, Elina; Kanepe-Lapsa, Iveta; Shestakova, Irina; Plotniece, Mara; Gosteva, Marina; Sobolev, Arkadij; Jansone, Baiba; Muceniece, Ruta; Klusa, Vija; Plotniece, Aiva


Book ID
120996716
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
701 KB
Volume
17
Category
Article
ISSN
1631-0748

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Synthesis and Calcium Channel Blocking A
✍ Rodolfo Lavilla; Teresa Gotsens; M.Carmen Santano; Joan Bosch; Antoni Camins; No πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 229 KB

A series of indolyldihydropyridines has been designed, synthesized, and evaluated in order to show the effect of the indole moiety and the role of the methyl groups at the 2 and 6 positions of the dihydropyridine ring in the calcium channel blocking activity. The results seem to show that these grou