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Synthesis and structures of deoxyribonucleoside analogues for triazole-linked DNA (TLDNA)

✍ Scribed by Tomoko Fujino; Nobuhide Tsunaka; Marine Guillot-Nieckowski; Waka Nakanishi; Takeaki Iwamoto; Eiichi Nakamura; Hiroyuki Isobe


Book ID
104097482
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
431 KB
Volume
51
Category
Article
ISSN
0040-4039

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Convergent synthesis of oligomers of tri
✍ Tomoko Fujino; Naomi Yamazaki; Hiroyuki Isobe πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 283 KB

A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ( TL DNA) has been developed. A one-pot procedure for desilylation of masked acetylene and the ensuing copper-catalyzed Huisgen coupling reaction between oligomers allowed the solution-phase synthesis