Convergent synthesis of oligomers of tri
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Tomoko Fujino; Naomi Yamazaki; Hiroyuki Isobe
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Article
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2009
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Elsevier Science
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French
β 283 KB
A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ( TL DNA) has been developed. A one-pot procedure for desilylation of masked acetylene and the ensuing copper-catalyzed Huisgen coupling reaction between oligomers allowed the solution-phase synthesis