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Efficient and improved synthesis of triazole-linked DNA (TLDNA) oligomers

✍ Scribed by Tomoko Fujino; Naomi Yamazaki; Ai Hasome; Kenta Endo; Hiroyuki Isobe

Book ID
113930384
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
397 KB
Volume
53
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES

Convergent synthesis of oligomers of tri
Convergent synthesis of oligomers of triazole-linked DNA analogue (TLDNA) in solution phase
✍ Tomoko Fujino; Naomi Yamazaki; Hiroyuki Isobe πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 283 KB

A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ( TL DNA) has been developed. A one-pot procedure for desilylation of masked acetylene and the ensuing copper-catalyzed Huisgen coupling reaction between oligomers allowed the solution-phase synthesis