Synthesis and Structure of Tolyporphin A O,O -Diacetate
β Scribed by Wang, Wengui; Kishi, Yoshito
- Book ID
- 127370099
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 79 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
Four monocyclic precursors were assembled in the total synthesis of the proposed structure 1-A of (+)-tolyporphin A O,O-diacetate (X=Ac). Comparison of the spectroscopic data demonstrated that synthetic tolyporphin O,O-diacetate did not match the O,O-diacetate prepared from natural (+)-tolyporphin A
1992 berichteten Moore und Mitarbeiter, daΓ» der lipophile Extrakt der cyanophyten Mikroalge Tolypothrix nodosa die Mehrfachresistenz (multi-drug resistance, MDR) [1] einer Vinblastin-resistenten Unterlinie einer humanen Eierstock-Adenokarzinomlinie umkehrt und daΓ» diese AktivitΓ€t grΓΆΓ»tenteils auf ei