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Synthesis and structure-activity relationships of new β-adrenoreceptor antagonists. Evidence for the electrostatic requirements for β-adrenoreceptor antagonists

✍ Scribed by V Kettmann; J Csöllei; E Račanská; P Švec


Book ID
103629562
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
993 KB
Volume
26
Category
Article
ISSN
0223-5234

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## Abstract A series of new phenoxypropanolamines with cyclic guanidine and isothiourea moieties has been prepared and investigated for non‐specific α‐ and α‐adrenoreceptor activity by receptor binding experiments on crude rat brain membrane. Some of them [9a, 10c] possess affinity for both β‐ and