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Synthesis and Receptor Binding Studies of (±)l-Iodo-MK-801

✍ Scribed by David J. Yang; Brian J. Ciliax; Marcian E. Van Dort; David L. Gildersleeve; Jean-Luc Pirat; Anne B. Young; Donald M. Wieland


Book ID
114421002
Publisher
Springer US
Year
1989
Tongue
English
Weight
502 KB
Volume
06
Category
Article
ISSN
0724-8741

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ChemInform Abstract: Aromatic Analogues
✍ Terre A. Sharma; Andrew J. Carr; Rebecca S. Davis; Ian J. Reynolds; Andrew D. Ha 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB

Aromatic Analogues of Arcaine Inhibit MK-801 Binding to the NMDA Receptor. -A novel series of analogues such as (VII) and (IX) are synthesized. The most active compound is a derivative of (IX) without the methoxy substituent. The structure-activity relationships are discussed.