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ChemInform Abstract: Aromatic Analogues of Arcaine Inhibit MK-801 Binding to the NMDA Receptor.

✍ Scribed by Terre A. Sharma; Andrew J. Carr; Rebecca S. Davis; Ian J. Reynolds; Andrew D. Hamilton


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Aromatic Analogues of Arcaine Inhibit MK-801 Binding to the NMDA Receptor.

-A novel series of analogues such as (VII) and (IX) are synthesized. The most active compound is a derivative of (IX) without the methoxy substituent. The structure-activity relationships are discussed.


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