Three derivatives of the DNA intercalating compound 9-aminoacridine, were prepared and radioiodinated for biological experiments. The compounds are the stannyl derivatives 3-{4-[3-(acridin-9-ylamino)-propoxy]-3-trimethylstannyl-phenyl}propionic acid and acridin-9-yl-{3-[4-(2-amino-ethyl)-2-trimethyl
Synthesis and Radioiodination of Some 9-Aminoacridine Derivatives
✍ Scribed by Senait Ghirmai; Eskender Mume; Cecile Henssen; Hadi Ghaneolhusseini; Hans Lundqvist; Vladimir Tolmachev; Stefan Sjöberg; Anna Orlova
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 154 KB
- Volume
- 2004
- Category
- Article
- ISSN
- 1434-193X
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## Abstract The finding that several derivatives of 9‐aminoacridine were deacridinylated in the presence of primary aliphatic amines during the solid phase synthesis of acridine–peptide conjugates prompted us to investigate the acridin‐9‐yl moiety transfer from a relatively low‐molecular acridine s