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Synthesis and properties of substituted 1-aryl-1,4-dihydro-4-oxopyrido[2,3-d]-pyrimidines

โœ Scribed by N. I. Shramm; M. E. Konshin


Book ID
112348705
Publisher
Springer US
Year
1985
Tongue
English
Weight
231 KB
Volume
21
Category
Article
ISSN
0009-3122

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Synthesis and properties of 2-substitute
โœ L. M. Demina; M. Yu. Gavrilov; M. I. Vakhrin; M. E. Konshin ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer US ๐ŸŒ English โš– 388 KB

Cyclization of 2- (N-acetyl-N-arylamino)nicotinonitriles in the presence of dry HCI gave 1-aryl-2-methyl-4-oxo-l,4-dihydropyrido[2,3-d]pyrimidines. It was shown that they are acylated by acetic anhydride, aroyl chlorides, and phenyl isocyanate at the methyl group and that with benzaldehyde they give